MK-677

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MK-677 5 mg — Growth Hormone & Metabolic Research

MK-677 is commonly used to refer to ibutamoren (MK-677), a non-peptide ghrelin-receptor agonist and growth-hormone secretagogue. It is studied for its effects on the growth hormone (GH)/IGF-1 axis, appetite signaling, energy metabolism, body composition, sleep physiology, and mechanisms involved in muscle and bone metabolism.

Research investigates how activation of the ghrelin receptor (GHS-R1a) influences endocrine and metabolic pathways, including changes in GH and IGF-1 signaling.

For laboratory and research use only. Not for human consumption.

Product Description

MK-677 5 mg — Growth Hormone & Metabolic Research

MK-677 is commonly used to refer to ibutamoren (MK-677), a non-peptide ghrelin-receptor agonist and growth-hormone secretagogue. It is studied for its effects on the growth hormone (GH)/IGF-1 axis, appetite signaling, energy metabolism, body composition, sleep physiology, and mechanisms involved in muscle and bone metabolism.

Research investigates how activation of the ghrelin receptor (GHS-R1a) influences endocrine and metabolic pathways, including changes in GH and IGF-1 signaling.

For laboratory and research use only. Not for human consumption.

Compound Information
MOLECULAR PROFILE
TypeSynthetic compound
CategoryResearch Compound
Purity≥99%
FormLyophilized powder
STORAGE REQUIREMENTS
Lyophilized (powder)

-20°C · 24+ months

Reconstituted

2–8°C · ~30 days

Certificate of Analysis

Third-party tested for purity and quality.

PURITY
0 %
Variant GLP3-RT 10mg
Lot # REF0001
Labeled 20mg
Actual 22.61mg
Tested APR 15, 2026

Coming soon

Research
New England Journal of Medicine

Triple–Hormone-Receptor Agonist GLP-3 (RT) for Obesity — A Phase 2 Trial

2023
DOI: 10.1056/NEJMoa2301972
· Jastreboff AM, et al.

New England Journal of Medicine

Triple–Hormone-Receptor Agonist GLP-3 (RT) for Obesity — A Phase 2 Trial

2023
DOI: 10.1056/NEJMoa2301972
· Jastreboff AM, et al.

New England Journal of Medicine

Triple–Hormone-Receptor Agonist GLP-3 (RT) for Obesity — A Phase 2 Trial

2023
DOI: 10.1056/NEJMoa2301972
· Jastreboff AM, et al.

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